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What are stem-cells?

Stem cells are the body's raw materials — cells from which all other cells with specialized functions are generated. Stem cells may have the potential to be grown to become new tissue for use in transplant and regenerative medicine. Researchers continue to advance the knowledge on stem cells and their applications in transplant and regenerative medicine.

Sources of Stem-cells

Embryonic Stem cells:- These stem cells come from embryos that are 3 to 5 days old. These are pluripotent stem cells, meaning they can divide into more stem cells or can become any type of cell in the body. This versatility allows embryonic stem cells to be used to regenerate or repair diseased tissue and organs.

Adult stem cells:- These stem cells are found in small numbers in most adult tissues, such as bone marrow or fat.

What is Stem-cell therapy?

It is also known as regenerative medicine. It promotes the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. It is the next chapter in organ transplantation and uses cells instead of donor organs, which are limited in supply. Researchers grow stem cells in a lab. These stem cells are manipulated to specialize into specific types of cells, such as heart muscle cells, blood cells or nerve cells

Diseases for which stem-cell therapy is most commonly performed are- Non-Hodgkin’s lymphoma, Leukemia, Stroke, Osteoarthritis, Rheumatoid Arthritis, Autoimmune Diseases, Spinal Cord Injury, Cardiac problems, Diabetes, stem cells for Hair Regrowth.

Top Stem Cell banks around the world

Americord
Cord Blood Registry
Cryocell
Viacord

Top Stem Cell banks in India

Lifecell International Pvt. Ltd.
Cord Life- (Cord-lining banking) :- Cord Life India, Kolkata.
Cryoviva India, Gurgaon.

Stem-Cell Expert

Dr. Lipi Singh

18 years of Work Experience

Vice President, Advancells Group| Regenerative Medicine| Freelance Consultant I Management| Leadership Quality Assurance & Regulatory Affairs| Medical Science Liaison (MSL)I Visit www.agingandhealthcare.com REGENERATIVE MEDICINE Trained & well Experienced in certification for M E D I C A L D E V I C E – Q U A L I T Y M A N A G E M E N T S Y S T E M (QMS ISO -13485:2016), MDR 2017 (IVD) & QMS ISO 9001:2015

Excerpts from her interview

Stem cell therapy is a form of regenerative medicine designed to repair damaged cells within the body by reducing inflammation and modulating the immune system (immunity of body ). This makes stem cell therapy a viable treatment option for a variety of medical conditions.

Stem cell therapies have been used to treat autoimmune, inflammatory, neurological, orthopaedic conditions and traumatic injuries. While stem cell therapy does not necessarily provide a cure for these conditions, the premise is to allow the body to heal itself well enough to mitigate the symptoms of the conditions for long periods. In many cases, this effect can substantially increase the quality of life for patients as well as delay disease progression.

People who might benefit from stem cell therapies include those with spinal cord injuries, type 1 diabetes, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, heart disease, stroke, burns, and osteoarthritis, Hair loss, Pain management, Chronic Obstructive Lung Disease. Paediatric cases: Autism , Cerebral ataxia , Cerebral palsy.

Stem cells offer great promise for new medical treatments. The popularity of stem cell treatments has significantly increased, thanks to its high effectiveness and recorded success rates of up to 80%.

India recently updated its guidelines on stem cell research (SCR), the National Guidelines for Stem Cell Research 2017. It was drafted under a collaborative effort from the Indian Council of Medical Research and Department of Biotechnology. The Government of India also set up a long-awaited National Apex Committee for Stem Cell Research and Therapy (NAC-SCRT) to oversee and monitor activities in this field. In 2014, the DCGI also announced that it would modify the Drugs and Cosmetics Act to treat “stem cells and cell-based products” as new drugs. Recently, on October 11, 2017, ICMR and DBT jointly updated the existing guidelines and released the NGSCR 2017. Some major amendments in this guideline include mandatory registration of the Institutional Committee for Stem Cell Research and the Institutional Ethics Committee (IEC) with NAC-SCRT and CDSCO, clinical trials only at institutes with registered IC-SCR and IEC, conducting studies only at Good Manufacturing Practice (GMP)- and Good Laboratory Practice (GLP)-certified facilities and clinical research undertaken by medical professionals registered with the Medical Council of India (MCI).

In India, the cost of getting a stem cell therapy can range between Rs. 15 lakhs to Rs. 25 lakh depending on the kind of transplant; whether it is an allogenic transplant or an autologous transplant.The average cost of stem cell therapy ranges from under $5,000 to over $25,000, depending the type and sources of the stem cells, the patient's medical condition, and the number of treatments required.

PRP is Expensive: Platelets are chock full of growth factors that aid in healing and repair of many different injuries throughout the entire body. This could be from a micro trauma in a blood vessel that the platelets patch up or it could be from a degenerative joint that needs a boost to get back on track. This makes platelet rich plasma a promising treatment option for a variety of diseases and injuries. This is a common misconception but easily proven false. PRP is even more cost-effective when you compare it to the other treatment options on the market.

Misconception: Stem cells may be rejected by the body: Truth- When the stem cells used to treat a condition are taken from the patient’s own body, there is very little risk of rejection or infection. This is one of the advantages of using adult stem cells to treat disease.

Misconception: Stem cells can cure all diseases: Truth- Studies have shown stem cells to be effective in the treatment of certain types of disease. They can improve and, in some instances, help in recovery. Research is ongoing to establish their efficacy in slowing or reversing the progression of certain diseases such as Parkinson’s, lupus, Alzheimer’s, diabetes, rheumatoid arthritis and other common diseases.

A dedicated team of physicians and scientists has been assembled for the stem cell treatment program

We are using the best stem cell technology in India with high % success treatment

Free of side effects and rejection

Avoiding allergic or immune reactions

There is no risk of contamination by transmissible diseases

Follow up and advised

Holistic approach along with stem cell therapy included nutritional, rehabilitation consultation

Treatment in Hospital set up with MCI certified Physician

Patient advocacy with stem cell expert medico scientist

There are several reasons why stem cell treatment is a healthier alternative.

Less Dependence on Medication: Chronic pain caused by the conditions we treat is routinely dealt with using medication. Excessive prescription of opiates to relieve pain has tragically cost many individuals their lives due to addiction. Medication doesn’t cure, it only makes problems easier to ignore. We don’t see this as a sustainable way to solve your problems

Less Invasive Treatment: Without the risks of surgery and the damage that it causes, you can recover naturally using your body’s own mechanisms. Utilizing your natural healing processes is clearly better than surgical intervention, which is why we always consider surgery as a last resort. No one denies that surgery works, but it should not be the first line of defence

Cost Savings: While stem cell treatment is not often covered by insurers, it can still be far less expensive than surgery with insurance. You also save by not having to pay for costly prescriptions. Even with repeat treatments, stem cells are still a more affordable option

Faster Treatment and Recovery: Treatment time is greatly reduced compared to surgical options. Surgery can take several hours, and you will need to be prepared for surgery beforehand. On the other hand, stem cell applications can take as little as half an hour. The cells are injected into the treatment area. Some local anaesthetic is applied first to ensure you feel no pain from the injection.

Stem cell therapy in India has shown several promising outcomes for many of the serious illnesses that are currently unresponsive to standard treatments. This is viable because of the incredible and special characteristics of stem cells. We understand the helplessness and stress that families go through after being diagnosed with a serious disease where conventional medical sciences have no treatment or very slow outcomes. For example , brain damage conditions such as Autism, Cerebral palsy, ADHD where parents have to undergo the pains of waiting decades, that too with very mild hope, are now able to see their kids moving towards normalcy, recognizing their parents – calling them Mom and Dad, socializing with other kids, able to do daily chores on of their own, shifting from special schools to normal school. Let us see one more example, the degenerative conditions like Dementia, Parkinson’s disease where you see your parents suffering and you are not able to do anything besides observing the progressive deterioration, now you can see them walking and playing with your kids. Similarly, stem cell therapies can solve many problems like serious spine injuries where patients have to be only on the bed, stroke, Chronic Kidney dysfunction, Arthritis, muscular dystrophy Delayed milestone, Mental retardation, motor neuron disease, TBI – Traumatic brain injury, etc.

Platelet-rich plasma (PRP) injections are gaining popularity for a variety of conditions, from sports injuries to hair loss. The treatment uses a patient’s own blood cells to accelerate healing in a specific area. PRP treatment can help support wound healing in trauma and joint injury. The technique can address male pattern baldness, stimulate the growth of hair transplants and enhance other cosmetic procedures. The results of PRP treatment are most noticeable after several weeks for joint injections and six months for scalp injections, and are not permanent; patients may require additional injections at the direction of their doctor. Because the treatments use a patient’s own tissues, PRP injections are safe and can be administered alone or used in conjunction with other procedures.

Dr. Lipi Singh

Excerpts from her interview

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Stem-Cell Therapy

Dr. Lipi Singh

Excerpts from her interview

How exactly stem cell therapy/treatment works?

Which are the Diseases that can be treated by this procedure?

For Which Disease the stem cells therapies are more effective?

What is the accuracy rate stem cell treatment provides?

Please brief some laws for stem cells in India and other countries

Approximate cost for stem cells treatment in India?

Common misconception about this treatment procedure?

Why to choose advancells centre for treatment? Top Centres in India and World

What are the things the patient should be aware of before undergoing treatment? Also long term benefits of stem cells treatment

How stem cell treatment in India is beneficial for foreigners?

More about Platelet rich Plasm a Therapy

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